Wu Chien-Shiung, radioactivity expert, known as the "First Lady of Physics"

She was a radioactivity expert who worked on the Manhattan Project and where she helped develop the process for separating metallic uranium into isotopes of uranium-235 and uranium-238 by gaseous diffusion. Her contributions in experimental physics were so important that she was compared to the chemist and physicist Marie Curie, and she was dubbed the "First Lady of Physics", the "Chinese Marie Curie" or the "Queen of Research Nuclear".

Source: Brown (Department of Physics)

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